Selected EGEN Presentations | | • 2008 | CRS 2008 " Development of a Novel Interleukin-12 Therapeutic for the Treatment of Ovarian Cancer ", Khursheed Anwer. | | | Beyond Genome 2008 " A Synthetic Gene Delivery System for IL-12: From Bench to Clinic ", Khursheed Anwer. | | | ACS 2008 " Functionalized Polymers for Gene Therapy: Discovery, Optimization and Clinical Development," Jeff Sparks. | | | ASCO 2008 " A Phase I Trial of Intraperitoneal EGEN-001, a Novel IL-12 Gene Therapeutic, Administered Alone or in Combination with Chemotherapy in Patients with Recurrent Ovarian Cancer ", Kellie S. Mathews, James E. Kendrick, Michael Straughn, Mack N. Barnes, Sharmila Makhija, Jason Fewell, Khursheed Anwer and Ronald D. Alvarez. J. Clin.Oncol. 26: 2008 (May 20 suppl; abstr 5572. | | | ASGT 2008 " Clinical Development of a Polymer-Based IL-12 Gene Therapeutic for the Treatment of Recurrent Ovarian Cancer ", Jason Fewell. | | | ASGT 2008 " Progress in Clinical Development of a Novel IL-12 Gene Therapeutic for the Treatment of Recurrent Ovarian Cancer ", Ronald D. Alvarez, Mack N. Barnes, Matthew L. Anderson, Souheil Saddekni, Sharmila Makhija, Ivan Maya, James E. Kendrick, Jason Fewell, Danny H. Lewis, and Khursheed Anwer, Mol Ther 16, S63 (#167), 2008. | | | ASGT 2008 " Optimization of Macromolecular Design for siRNA Delivery ", Jeff Sparks, Gregory Slobodkin, Majed Matar, Jason Fewell, Jennifer Rice, Elaine Brunhoeber, Casey Pence, Diane McClure, Khursheed Anwer, Mol Ther 16, S318 (#855), 2008. | | | ORS 2008 " Non-viral Gene Therapy Approaches for Osteoarthritis ", Jason G. Fewell, Majed M. Matar, Jennifer S. Rice, Renwen Zhang and Khursheed Anwer, Transactions 33 (1191), 2008. | | • 2007 | New Directions for Drug Delivery 2007 "Novel Therapies for the Treatment of Cancer Using Nucleic Acid Delivery", Khursheed Anwer. | | | ASGT 2007 "Treatment of Metastatic Renal Cell Cancer Using Multiple IV Administration of IL-12 Plasmid Nanocomplexes", Jason Fewell, Jennifer Rice, Miranda Hickman, Majed Matar, Elaine Brunhoeber, Casey Pence, Gregory Slobodkin, Danny Lewis and Khursheed Anwer, Mol Ther 15, S65 (#170), 2007. | | | ASGT 2007 "Progress in the Clinical Development of a Novel IL-12 Gene Therapeutic for the Treatment of Recurrent Ovarian Cancer", Khursheed Anwer, M. Barnes, M. Anderson, C. McCombs, S. Saddekni, S. Makhija, I. Maya, Jason Fewell, M. Amsbury-Janat, Danny Lewis and Ronald Alvarex, Mol Ther 15, S69 (#182), 2007. | | | AACR 2007 "Use of Interleukin-12 Plasmid Nanocomplexes as a General Treatment Strategy Against Disseminated Peritoneal Malignancies", Jason Fewell, Jennifer Rice, Majed Matar, Elaine Brunhoeber, Casey Pence, Gregory Slobodkin, Danny Lewis and Khursheed Anwer, Proc. Amer. Assoc. Cancer Res. 48:3304, 2007. | | | AAPS 2007 "A Method of Large-scale Manufacturing of Nucleic Acids with Cationic Polymers", Majed Matar, Jason Fewell, Danny Lewis and Khursheed Anwer, AAPS Journal 2007, 9(S2). | | • 2006 | "Safety & Tolerability of Intraperitoneal Delivery of IL-12 Plasmid/Lipopolymer Complexes for the Treatment of Recurrent Ovarian Cancer", Alvarez RD, Barnes MN, Anderson, ML., Margit Maria Janat-Amsbury, McCombs C, Makhija S, Fewell J, Lewis DH, Anwer K., IGCS, Santa Monica, International Gynecologic Cancer Society Meeting 2006 | | | "Effect of Microcirculation on Transfection Efficiencies of Gene-Delivering Nanoparticles", Balabhaskar P, Pant K., Fewell J., Anwer K., Kiani ME., and Sundaram, S., Proceedings of the Biomedical Engineering Society, Biomedical Engineering Society Annual Meeting 2006 | | | "Polymeric Transfection Reagents for shRNA Delivery in vitro and in vivo", Fewell GD., Matar M., Fewell JG., Moore T., DuBreuil R. , RNAi Europe, Prague, Czech Republic, RNAi Europe Annual Meeting 2006 | | | "Combination Interleukin-12 Intraperitoneal Gene Therapy with Chemotherapy for Treatment of Disseminated Ovarian Cancer", Proc. Amer. Assoc. Cancer Res. 47:2112, 2006. Fewell JG, Rice JK, Matar MM, Slobodkin G, Lewis DH, Anwer K., American Association for Cancer Research Annual Meeting 2006 | | | "Safety and toxicity following intraperitoneal injection of murine interleukin-12 plasmid formulated with a novel polymeric delivery system", Mol. Ther. 13, S109 (#287), Fewell JG, Rice J, Matar M, Anwer K., American Society of Gene Therapy Annual Meeting 2006 | | | "Biodistribution and Clearance Following Intraperitoneal Injection of Murine Interleukin-12 Plasmid Formulated with a Novel Polymeric Delivery System", Mol. Ther. 13, S109 (#286), Brunhoeber E, Matar M, Anwer K, Fewell JG., American Society of Gene Therapy Annual Meeting 2006 | | | "A Phase I Clinical Trial of an IL-12 Gene Plasmid Formulated with a Novel Ipopolymeric Gene Delivery System for Intraperitoneal Treatment of Recurrent Ovarian Cancer", Mol. Ther. 13, S109 (#1105), 2006. Alvarez RD, Barnes MN, McCombs C, Makhija S, Fewell JG, Lewis DH, Anwer K., American Society of Gene Therapy Annual Meeting 2006 | | • 2005 | "Novel Functionalized Polymeric Formulation for use in Delivering Therapeutic Genes for the Treatment of Solid Tumors", Mol. Ther. 11: S110. Fewell, J., Matar, M., Rice, J., Slobodkin, G., Hovanes, B. and Anwer, K., American Society of Gene Therapy Annual Meeting 2005 | | | "Functionalized Multi-Block Co-Polymers of Short Length Linear Polyethylenimines for Safe and Efficient Gene Transfer", Mol Ther. 11: S90. Slobodkin, G., Matar, M, Ramsey, A., Fewell, J., Brunhoeber, E. and Anwer, K., American Society of Gene Therapy Annual Meeting 2005 | | | "Preclinical & Clinical Development of a Biocompatible Gene Delivery Polymer for Treatment of Cancer", Anwer K., Advances in Tissue Engineering Conference, Rice University, Houston, TX. | | | "A Novel Functionalized Polymeric Formulation for use in Delivering Therapeutic Genes for the Treatment of Solid Tumors", Fewell J., 8th Annual Meeting of the American Society of Gene Therapy, St. Louis, MO. | | | "Preclinical Development of a Biocompatible Non-Viral Gene Delivery System for Gene Therapy of Cancer", Anwer K., 12th International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, Utah. | | • 2004 | "Polymeric Delivery Systems for Gene Therapy of Cancer", Anwer K., Advances in Tissue Engineering Conference and Workshop, Rice University, Houston, TX. | | • 2003 | "Gene Therapy Strategies Using Polymeric Carrier Systems", Anwer K., 7th U.S.-Japan Symposium on Drug Delivery Systems. Lahina, Hawaii. | | • 2003 | "Therapeutic Applications of Non-Viral Gene Delivery Technologies", Anwer K., Advances in Tissue Engineering Conference and Workshop, Rice University, Houston, TX. |
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